Expresión de búsqueda: HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K 
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Descriptor Inglés:   Heterogeneous-Nuclear Ribonucleoprotein K 
Descriptor Español:   Ribonucleoproteína Heterogénea-Nuclear Grupo K 
Descriptor Portugués:   Ribonucleoproteínas Nucleares Heterogêneas Grupo K 
Categoría:   D12.776.157.725.813.750.500
D12.776.260.268
D12.776.664.962.813.750.500
Definición Inglés:   A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties. 
Nota de Indización Inglés:   see SCR for specific hnRNP entries
Nota Histórica Inglés:   2003; use HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K (NM) 1994-2002; for HNRNP K use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1994-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   37415 
Identificador Único:   D034641 

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